Leukopenia and Leukocytosis in Splenectomized Rabbits

Some Data on Mechanism of Leukopenia and Leukocytosis following Irradiation.

T HE LEUKOPENIA developing some days after a high dosage of ionizing irradiation is apparently due to direct injury of the bone marrow. On tile other hand, the appearance of leukocytosis before leukopenia develops mdicates that other factors may influence the level of circulating leukocytes in that phase. Tile short course of this initial leukocytosis suggests the possibility of an increased pe...

Leukocytosis in rabbits with diet-induced atherosclerosis.

In cholesterol-fed rabbits the extent of monocyte involvement in atherogenesis may be influenced by the level of circulating leukocytes during hypercholesterolemia. We characterized the leukocytosis in rabbits fed either a 0.25% or a 0.1% cholesterol-enriched diet (0.25% or 0.1% rabbits, respectively). Circulating leukocytes were elevated by 1 week of feeding, and the elevation was sustained fo...

Observations on Heinz bodies in normal and splenectomized rabbits.

Treatment effect of low intensity pulsed ultrasound on leukopenia induced by cyclophosphamide in rabbits.

OBJECTIVE This study aims to examine the effects of low intensity pulsed ultrasound (LIPUS) on leukopenia induced by cyclophosphamide in a rabbit model. METHODS The leukopenia model in New Zealand rabbit was established by injecting cyclophosphamide into the ear vein. Forty leukopenia model rabbits were randomly allocated to control group (n = 20) and LIPUS group (n = 20). LIPUS group underwe...

Splenectomized versus non-splenectomized patients with thalassemia major. Echocardiographic comparison.

OBJECTIVE To study the effect of splenectomy in patients with thalassemia major on the cardiovascular system through echocardiographic study. METHODS A prospective, cross sectional study was carried out from December 2006 to December 2007. Patients from the Thalassemia Center in the Maternity and Children's Hospital, Madina, Kingdom of Saudi Arabia, were screened by means of history, physical...